New investigators in glycoscience.

Medical Glycoscience

Recent applications of click chemistry for the functionalization of gold nanoparticles and their conversion to glyco-gold nanoparticles

Glycoscience, despite its myriad of challenges, promises to unravel the causes of, potential new detection methods for, and novel therapeutic strategies against, many disease states. In the last two decades, glyco-gold nanoparticles have emerged as one of several potential new tools for glycoscientists. Glyco-gold nanoparticles consist of the unique structural combination of a gold nanoparticle...

A novel I-branching β-1,6-N-acetylglucosaminyltransferase involved in the human blood group I antigen expression

National Institute of Advanced Industrial Science and Technology (AIST), Glycogene Function Team, Research Center for Glycoscience (RCG), Tsukuba, Ibaraki, Japan. JGS Japan Genome Solutions, Inc., Hachioji, Tokyo, Japan. Fujirebio Inc., Frontier Research Division, Hachioji, Tokyo, Japan. Jichi Medical School, Division of Stem Cell Regulation, Minamikawachi, Tochigi, Japan. Amersham Biosciences ...

Glycoscience@Synchrotron: Synchrotron radiation applied to structural glycoscience

Synchrotron radiation is the most versatile way to explore biological materials in different states: monocrystalline, polycrystalline, solution, colloids and multiscale architectures. Steady improvements in instrumentation have made synchrotrons the most flexible intense X-ray source. The wide range of applications of synchrotron radiation is commensurate with the structural diversity and compl...

Glycoscience finally comes of age.

Glycoscience—the study of the complex carbohydrates on the surface of proteins and lipids—has long been the neglected stepchild of molecular biology. Although genomics, proteomics and now systems biology have become hot topics of biomedical research, attracting both researchers and funding, glycoscience has played a rather minor role. Once of little interest to understanding biology on a larger...

Glycosylation of Amino Acids and Efficient Synthesis of Glycosphingolipids

Glycoscience is an emerging field of science that focuses on the study of the structure, biosynthesis, biology, and evolution of saccharides (sugars). It covers a broad range of subjects including microwave-assisted synthesis as well as sphingolipid synthesis. In this field, knowledge is limited due to the complexity of carbohydrates and their derivatives. Therefore, it is all the more importan...